Publications

• Willems J, de Jong APH, Scheefhals N, Mertens E, Catsburg LAE, Poorthuis RB, de Winter F, Verhaagen J, Meye FJ, MacGillavry HD. ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons. PLoS Biol. 2020 10;18(4):e3000665.
• Scheefhals N, Catsburg LAE, Westerveld ML, Blanpied TA, Hoogenraad CC, MacGillavry HD. Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5. Cell Rep. 2019;29(2):258–269
• Lindhout FW, Cao Y, Kevenaar JT, Bodzęta A, Stucchi R, Boumpoutsari MM, Katrukha EA, Altelaar M, MacGillavry HD, & Hoogenraad CC. (2019). VAP-SCRN1 interaction regulates dynamic endoplasmic reticulum remodeling and presynaptic function. The EMBO journal, 38(20)
• Berdenis van Berlekom A, Muflihah CH, Snijders GJLJ, MacGillavry HD, Middeldorp J, Hol EM, Kahn RS, de Witte LD. Synapse Pathology in Schizophrenia: A Meta-analysis of Postsynaptic Elements in Postmortem Brain Studies. Schizophr Bull. 2019 Jun 13:sbz060
• Koopmans F, van Nierop P, Andres-Alonso M,…, MacGillavry HD,…, et al. SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse. Neuron. 2019;103(2):217–234.e4
• Ormel PR, Vieira de Sá R, van Bodegraven EJ, Karst H, Harschnitz O, Sneeboer MAM, Johansen LE, van Dijk RE, Scheefhals N, Berdenis van Berlekom A, Ribes Martínez E, Kling S, MacGillavry HD, van den Berg LH, Kahn RS, Hol EM, de Witte LD, Pasterkamp RJ. (2018) Microglia innately develop within cerebral organoids. Nat Commun. 9(1):4167
• MacGillavry HD, Hoogenraad CC. (2018) Membrane trafficking and cytoskeletal dynamics in neuronal function. Mol Cell Neurosci 91:1-2
• Scheefhals N, MacGillavry HD. (2018) Functional organization of postsynaptic glutamate receptors. Mol Cell Neurosci 91:82-94.
• Post H, Penning R, Fitzpatrick MA, Garrigues LB, Wu W, MacGillavry HD, Hoogenraad CC, Heck AJ, Altelaar AF. (2017) Robust, Sensitive, and Automated Phosphopeptide Enrichment Optimized for Low Sample Amounts Applied to Primary Hippocampal Neurons. J Proteome Res. 16(2):728-737.
• Tang AH, Chen H, Li TP, Metzbower SR, MacGillavry HD & Blanpied TA. (2016) A trans-synaptic nanocolumn aligns neurotransmitter release to receptors. Nature 536, 210-214.
• Li TP, Song Y, MacGillavry HD, Blanpied TA & Raghavachari S. (2016) Protein crowding within the postsynaptic density can impede the escape of membrane proteins. J Neurosci 36, 4276-4295
• MacGillavry HD, Kerr JM, Kassner J, Frost NA & Blanpied TA. (2016) Shank-cortactin interactions control actin dynamics to maintain flexibility of neuronal spines and synapses. Eur J Neurosci 43, 179-19
• MacGillavry HD & Hoogenraad CC. (2015) The internal architecture of dendritic spines revealed by super-resolution imaging: What did we learn so far? Exp Cell Res 335, 180-186.
• Lu HE, MacGillavry HD, Frost NA & Blanpied TA. (2014) Multiple spatial and kinetic subpopulations of CaMKII in spines and dendrites as resolved by single-molecule tracking PALM. J Neurosci 34, 7600-7610.
• MacGillavry HD & Blanpied TA. (2013) Single-molecule tracking photoactivated localization microscopy to map nano-scale structure and dynamics in living spines. Curr Protoc Neurosci 23,2.20.1-2.20.19.
• MacGillavry HD, Song Y, Raghavachari S & Blanpied TA. (2013)  Nanoscale scaffolding domains within the postsynaptic density concentrate synaptic AMPA receptors. Neuron 78, 615-622.
• MacGillavry HD, Kerr JM & Blanpied TA (2011) Lateral organization of the postsynaptic density. Mol Cell Neurosci 48, 321-331.
• Van Kesteren RE, Mason MR, MacGillavry HD, Smit AB & Verhaagen J (2011) A gene network perspective on axonal regeneration. Front Mol Neurosci 4, 46.
• Geeven G*, MacGillavry HD*, Eggers R, Sassen MM, Verhaagen J, Smit AB, de Gunst MC & van Kesteren RE (2011) LLM3D: a log-linear modeling-based method to predict functional gene regulatory interactions from genome-wide expression data. Nucleic Acids Res 39, 5313-5327. *contributed equally.
• MacGillavry HD, Cornelis J, van der Kallen LR, Sassen MM, Verhaagen J, Smit AB & van Kesteren RE (2011) Genome-wide gene expression and promoter binding analysis identifies NFIL3 as a repressor of C/EBP target genes in neuronal outgrowth. Mol Cell Neurosci 46, 460-468.
• MacGillavry HD*, Stam FJ*, Sassen MM, Kegel L, Hendriks WT, Verhaagen J, Smit AB & van Kesteren RE (2009) NFIL3 and cAMP response element-binding protein form a transcriptional feedforward loop that controls neuronal regeneration-associated gene expression. J Neurosci 29, 15542-15550.*contributed equally.
• Court FA, Hendriks WT, MacGillavry HD, Alvarez J & van Minnen J (2008) Schwann cell to axon transfer of ribosomes: toward a novel understanding of the role of glia in the nervous system. J Neurosci 28, 11024-11029.
• Stam FJ, MacGillavry HD, Armstrong NJ, de Gunst MC, Zhang Y, van Kesteren RE, Smit AB & Verhaagen J (2007) Identification of candidate transcriptional modulators involved in successful regeneration after nerve injury. Eur J Neurosci 25, 3629-3637.
• Derksen PW, Tjin E, Meijer HP, Klok MD, MacGillavry HD, van Oers MH, Lokhorst HM, Bloem AC, Clevers H, Nusse R, et al. (2004) Illegitimate WNT signaling promotes proliferation of multiple myeloma cells. Proc Natl Acad Sci U S A 101, 6122-6127.

Book chapters

• Frost NA*, MacGillavry HD*, Lu HE & Blanpied TA. (2014). Live-cell PALM of intracellular proteins in neurons. Imaging nanoscale dynamics at synapses. *contributed equally.

• Verhaagen J, Van Kesteren RE, Bossers KA, MacGillavry HD, Mason MR & Smit AB (2012) Molecular target discovery for neural repair in the functional genomics era. Handb Clin Neurol 109, 595-616.