People

Harold MacGillavry, PhD

hdmacgillavryHarold MacGillavry studied Medical Biology at the University of Amsterdam, and obtained his PhD (2010) at VU University Amsterdam with Dr. Ronald van Kesteren, Prof. Dr. Guus Smit, and Prof. Dr. Joost Verhaagen. He then joined the lab of Dr. Tom Blanpied at the University of Maryland Baltimore (2010 – 2014). Here, he used live-cell, single-molecule imaging approaches to study the dynamic organization of neurotransmitter receptors and structural proteins at neuronal excitatory synapses. In 2013, he received an ALW-VENI grant from NWO and a Return-to-Europe fellowship from FEBS. He then joined the Cell Biology department at Utrecht University in 2014. In 2016 he received a NARSAD Young Investigator Award, and a Starting Grant from the European Research Council (ERC).

 

Nicky Scheefhals, PhD student

Photo NickyNicky Scheefhals studied Molecular and Cellular Life Sciences at the University of Utrecht and received her MSc degree in 2016. She received a Quantitative and Computational Life Sciences (Qbio) grant from NWO’s Graduate Programme and started her PhD in the lab of Dr. Harold MacGillavry in Oktober 2016. She has great interest in understanding fundamental processes in brain functioning and is highly enthusiastic about the opportunity to study this at a nanoscopic scale using advanced super-resolution imaging techniques. This nicely fits with her main focus on resolving the dynamic positioning of glutamate receptors at excitatory synapses crucial to efficient neuronal signaling.

 

 

Lisa Catsburg, PhD student

FullSizeRenderLisa Catsburg studied Molecular Neurosciences at the University of Amsterdam and obtained her MSc degree in 2017. The same year she started her PhD in the group of Dr. Harold MacGillavry. She is interested in understanding the molecular machinery underlying neuronal plasticity and excitability. In line with this, her project focusses on the molecular mechanisms regulating postsynaptic receptor trafficking at glutamatergic synapses. Using a variety of molecular and advanced microscopy techniques she will investigate these mechanisms through space and time in the greatest detail.

 

 

 

Jelmer Willems, PhD student

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Jelmer Willems studied Molecular and Cellular Life Sciences at the University of Utrecht. After obtaining his MSc degree in 2017, he started his PhD in the group of Dr. Harold MacGillavry. He is interested in the molecular architecture of the excitatory synapse. Using a combination of molecular techniques and advanced single-molecule microscopy, his project aims to understand the spatial distribution of neurotransmitter receptors at excitatory synapses and how this relates to synaptic strength.

 

 

 

 

Anna Bodzeta, postdoc

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Anna Bodzęta studied Biophysics at the Jagiellonian University in Krakow and received her MSc degree in 2012. For her PhD study, Anna joined the lab of Prof. Dr. Jürgen Klinaguf at Institute of Medical Physics and Biophysics, University of Münster and obtain her PhD degree in 2017. During PhD study, she investigated the molecular mechanism linking regulation of vacuolar H+-ATPase activity and synaptic vesicle exocytosis in hippocampal neurons using various fluorescence microscopy techniques. In November 2017, she started her postdoctoral training in the lab of Dr. Harold MacGillavry. Anna is interested in understanding the molecular mechanisms underlying synaptic organization and function with focus on presynaptic terminals. In line with this, her project focuses on the nanoscale organization of presynaptic glutamate receptors and their role in synaptic transmission.

 

 

 

Manon Westra, PhD student

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Manon Westra studied Neurosciences at the VU University in Amsterdam and obtained her MSc degree in 2017. At the end of that year, she started her PhD in the group of Dr. Harold MacGillavry. She is interested in the molecular mechanisms behind brain functioning and the different ways of visualizing the nanoscale structures in the brain. Her project focusses on understanding the synaptic membrane organization. She will investigate the dynamics of synaptic membrane components using advanced super-resolution microscopy techniques.

 

 

 

Arthur de Jong, postdoc